Preheat oven to 350 degrees F. Line a large rimmed baking sheet with foil and coat it with nonstick cooking spray.
Heat the olive oil in a medium skillet. Add the onions, garlic, Italian seasoning, salt, and pepper and cook over MEDIUM-LOW heat, stirring occasionally, for 4 to 5 minutes, until the onions are tender but not browned. Reduce heat to LOW and add the Worcestershire sauce and tomato paste. Cook, stirring constantly, until well combined. Remove from the heat and allow to cool slightly.
In a large bowl, whisk the eggs. Mix in the panko and milk until well combined. Break up the ground beef and add it to the bowl along with the slightly cooled onion mixture. Mix lightly, starting with a wooden spoon and ending with your hands (don’t overmix or the meatloaf will be dense).
Divide the mixture into 8 portions and shape each portion into a small loaf, offsetting them to fit on the prepared sheet pan. Bake for 20 minutes.
Meanwhile, in a separate small bowl, combine the ketchup, BBQ sauce, and mustard. Remove the baking sheet from the oven and spoon the sauce evenly over the tops. Return the pan to the oven and bake for an additional 20 to 25 minutes, or until the internal temperature has reached 165 degrees F.
Garnish with fresh herbs, if desired, and serve warm.